This paper investigates on generation and mitigation of common-mode noise for differential traces crossing other traces in dual strip line structure. This paper provides new structures to mitigate common-mode noise. The structure simulated by 3-D full-wave simulator HFSS and CST. Through two simulation software to compare and verify each other, in frequency domain compared by differential-to-common mode conversion, in time domain measured by common-mode noise. The mitigation scheme provided in this paper is that when the upper and lower layer transmission lines are crossed, the crossing angle of the original structure is changed from 45 degrees to 90 degrees and the weak coupling is changed to strong coupling. No matter time domain or frequency domain can be observed that the mitigation scheme significantly reduce the common-mode noise. In order to verify the proposed structure, the test board will be tested and verified by computer simulation and measurement. Finally, the design rule will be proposed to mitigate common-mode noise.