原子力顯微鏡的應用探討-以力學為例

Application of atomic force microscopy-examples of mechanics

陳智凱(Chih-Kai Chen)

指導教授 ： 傅傳博

國立暨南國際大學/科技學院/應用化學系生物醫學碩士班/碩士(2014年)

摘要

近年來原子力顯微鏡被廣泛的應用在測量各種材料與生物表面的力學性質，其幾乎不破壞樣品的性質，以及能在空氣、液體環境進行偵測，很適合應用在容易受環境影響且須保有水分的活體生物。
本篇使用原子力顯微鏡觀察酵母在水溶液中的表面形貌與力學性質，利用 Si3N4探針對酵母與載玻片進行力曲線測量，並計算楊氏係數(Young's modulus)與作用力，進行數據的定量分析。

關鍵字

原子力顯微鏡 ； 楊氏係數

並列摘要

In the recent years, the atomic force microscopy (AFM) has been widely used to study the physical properties of many materials and cells. It could measure in liquid environment
and without destroying the samples. The AFM is suitable for application to living organisms that are easily affected by the environment and moisture indispensable.
In this thesis, we use the atomic force microscopy to study the topography and the mechanical properties of the yeast cells in aqueous solutions. The unmodified probe was used to analyze the force curve of the yeast cells and slides, and calculate the adhesion forces and Young’ s modulus by Hertz model.

並列關鍵字

Atomic force microscopy ； Young’ s modulus

參考文獻

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