在2004年的全球惡性腫瘤統計當中,口腔癌已成為全球主要死因中第十名,而皮膚癌亦為全球主要死因第十六名。本研究的目的為開發一套使用電阻抗技術分析出大面積病變表層組織範圍所在並成像的檢測系統。在本研究的系統設計中分為硬體與軟體兩部份;而硬體又細分為類比多工器電路、生物電阻抗分析電路、類比轉數位電路以及RS-232資料發送電路共四種電路;軟體部分則細分為RS-232資料接收程式與生物電阻抗二維成像程式兩部份。設計開發之後對各項電路與程式進行各種準確性評估;整合完成後則開始進行模擬測試。由各評估結果可得知,各項電路與程式部份的準確性接近理論值;另外由模擬測試結果發現,可藉由影像直觀地區分出正常表層組織與病變表層組織範圍所在。總而言之,生物阻抗量測技術應用於表層組織的病變檢測具有相當的潛力與可行性。
In Taiwan, 35.9 out of 100,000 people diagnosed with oral cancer, just second to New Guinea and Solomon. According to the statistics reported by the Department of Health, oral and skin cancer ranked sixth and twenty-first positions respectively in major cause of cancer death for four consecutive years in Taiwan. Currently non-invasive oral and skin cancer diagnostic products are very scarce, and the equipment is very expensive and heavy. Therefore, the purpose of this study is to develop a 2-dimensional image measurement system based on bioimpedance technique. The system has been evaluated with the averaged percentage error of about 5.2% ± 2.8%. Finally, we can use this system to distinguish normal and morbid tissues by the 2-dimensional image.