升壓型直流脈波高壓電路設計與實現

The Design and Realization of The DC-DC Boost Converter Pulse High Voltage Electric Circuit

高子勛(Tzu-Shiun Kao)

指導教授 ： 孫台平

國立暨南國際大學/科技學院/光電科技碩士學位學程/碩士(2014年)

摘要

本論文研究，主要為設計一組可調整之高壓脈波衝擊產生器，可應用於細胞膜電穿孔技術，由於高壓電穿孔儀器或其設備造價昂貴零件維護不易，本研究希望能開發出一套既輕巧低成本易維修，且攜帶方便可調整電壓與脈波之電穿孔儀，擺脫現有對電脈衝穿孔儀，笨重且價格昂貴的既定印象，期使本研究，所設計之可調整之高壓脈波衝擊產生器，轉變為一種極具機動性、方便性、與電壓可設定之實驗研究器材。
論文中所設計之調整高壓脈波衝擊產生器，已可成功升壓，並依不同之實驗條件設定，電壓設定範圍為100V~800V，高壓是由升壓轉換器(Boost converter)的方式，配合脈波寬度調變技術(PWM)與所構成之高壓電路，其中電壓回授部份採用遲滯電壓比較器方式，進行電壓回授與輸出比較，可設定電壓範圍100V~800V，脈波部份設定範圍0.1ms~10ms之脈波選擇。

關鍵字

DC/DC升壓型轉換器 ； 脈波寬度調變 ； 遲滯比較器 ； 電穿孔

並列摘要

In this thesis, the purpose is designing of a high-voltage pulse of adjustable shock generator which can be applied to the cell membrane electroporation technology. Because high voltage piercing instruments and equipment parts are expensive which also cause maintenance difficulties. This research study is to develop a set of low cost adjustable voltage pulse of electroporation device with the advantages of easy maintenance and lightweight that is easy to carry with. By getting rid of the existing impression of an electroporation device-bulky and expensive, the study of this design of the high-voltage pulse adjustable wave impulse generator could turn into a experimental research equipment with high mobility and convenience.
In this thesis, the design of the high-voltage pulse adjustment shock generator has been successfully boost according to different set of experimental conditions； the high voltage is determined by the boost converter with pulse width modulation technique (PWM) and the high voltage circuit constituted a voltage range from 100V to 800V. With the technique of the hysteresis voltage comparator creates feedback voltage compared with the output voltage, the voltage range can be set within 100V ~ 800V with choices of pulse width between 0.1ms ~ 10ms.

並列關鍵字

DC-DC Boost Converter ； PWM ； Hysteresis Comparator ； Electroporation

參考文獻

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