Even though the Taiwan government earns the high reputation for the medical insurance among the worlds, the nurses often complain the burnout because of the overworking. The measurement of vital signs is the most fundamental routines in medical facilities. Physicians use the vital sign to have right treatment to the patients. Thus, it is very crucial to record the vital signs correctly even though the process is tedious and time consuming. This research tries to utilize the wireless property of RFID to transmit the vital signs to a customized medical system automatically. The collected vital signs can also be further analyzed by data mining approach to predict the occurrence of serious disease. It is hope that this research can provide the medical automation to alleviate the nurses’ working load and ensure the patients’ health.