可攜式恆電位儀與電化學生物感測器之整合研究

The Study of Portable Potentiostat and Electrochemical Biosensors Integration

張志弘(Chih-Hung Chang)

指導教授 ： 陳朝烈 ； 黃俊岳

崑山科技大學/工程學院/電子工程研究所/碩士(2007年)

https://doi.org/10.6828/KSU.2007.00006

摘要

本論文主要研究發展一個低成本的可攜帶式恆電位儀，來模擬商用恆電位儀之功能，並與其他研究夥伴所設計的不同之電化學生物感測晶片做整合，以應用於家庭看護系統。本論文主要針對電化學中常應用的三種量測系統做設計，即是：電位量測、恆電位電流量測和循環伏安法(CV，Cyclic Voltammetry)掃描三種量測系統。
在恆電位電流量測系統中與膽紅素感測晶片做整合實驗的結果，顯示可攜式恆電位儀在加入不同濃度待測物時，感測晶片上量測的電流變化，與商用恆電位儀有相同的反應趨勢；而在循環伏安法系統中與白蛋白感測晶片和膽紅素感測晶片做整合實驗的結果，則是顯示與商用恆電位儀所量測的反應電位值已在可接受之準確值範圍內。
本研究中所發展的可攜式恆電位儀與商用恆電位儀相較之下，具有適當的準確性、體積小、重量輕、價格便宜與高可攜帶性等特點，並未來將與電化學生物感測晶片整合來實現家庭看護系統。

關鍵字

恆電位儀 ； 生物感測器 ； 電化學

並列摘要

In this thesis, we study the design and implementation of a low cost portable potentiostat to mimic the function of commercial potentiostats. Integrating with the different electrochemical biosensors developed by our research partners, the whole system can be applied in the home-care system. The proposed portable potentiostat performs three general electrochemical measurement functions including potentiometric, amperometric, and cyclic voltammetry (CV) measurements.
Considering the experimental results of amperometric potentiostat with the bilirubin sensor, when the concentration of the bilirubin changes, we can observe that the biosensor currents measured by the proposed potentiostat have the same trends as those measured by the commercial potentiostat. Meanwhile, according to the experimental results of cyclic voltammetry potentiostat with albumin sensor and bilirubin sensor, the proposed potentiostat’s performance achieves the same accuracy as the commercial potentiostat’s.
In this thesis, in comparison with the commercial potentiostat, the proposed potentiostat has the merits of moderate accuracy, small size, light weight, low cost, and high portability. In the future, we will integrate the proposed potentiostat with biosensors to realize the home-care system in daily life.

並列關鍵字

Electrochemical ； Biosensor ； Potentiostat

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