Inconel 617 is a structural-material candidate for the intermediate heat exchanger used in the Generation IV Reactor Power Plant. It is important to investigate its strain rate effect. We use both the high-flux neutrons at the Spallation Neutron Source and the novel data acquisition with reduction technique at the VULCAN Engineering Diffractometer to create in-situ experimental environment. Upon different strain rates, a change in the lattice modulus was discovered. In general, the greater Young’s moduli are typically in proportional to the bulk strain rate. The trend of the lattice-modulus transition is opposite to the changes of bulk modulus as a function of the strain rates. We also apply molecular dynamics (MD) simulation and transmission electron microscopy (TEM) to compare the measured strain rate effect.