This study was used the fire modeling software Fire Dynamics Simulator (FDS) to simulate the tutorial school to have the fire. The three circumstances were either changed the compartmented material or the classroom door closure or not. Finally this study aims at examination the disaster relief strategies resulted from the study findings. From the simulating results showed that in the condition of fire flame spreading the close of classroom door having the best effects to impediment flame spreads. In the thick smoke and the visibility part, close the classroom door to be able having effective impediment thick smoke. In addition, the results showed that fire resistant material to have effective control thick smoke production. The final remark from this study demonstrated to be having good fire protection knowledge, establishes the essential fire protection building materials, and escapes to seek shelter needing closure door to impediment fire intensity and the thick smoke. These strategies have enormous help for the personnel escapes to seek shelter.