非離子型界面活性劑在濃懸劑型配方殺菌劑之研究

Application of non-ionic surfactant on the formulations of the Suspo-Emulsion disinfectant

賴建志(Chien-Chih Lai)

指導教授 ： 陳齊聖

朝陽科技大學/理工學院/應用化學系/碩士(2009年)

摘要

本試驗選擇之原體：賓克隆 Pencycuron於業界中有粉劑DP(Dustable powder)、水懸劑 SC(Suspension concentrate)、可濕性粉劑WP(Wettable powder)等三種劑型產品；待克利 Difenoconazole於業界中有乳劑 EC(Emulsifiable concentrate)、水懸劑 SC(Suspension concentrate)、水分散性粒劑 WG(Water dispersible granules)等三種劑型產品。以對環境之友善度、現今施用之劑型，提升藥劑之效能及節省勞力等前提下，故測試以賓克隆 Pencycuron之殺菌劑原體製備水懸劑 SC(Suspension concentrate)及待克利 Difenoconazole之殺菌劑原體製備微乳劑 ME(Micro- emulsion)及水基乳劑 EW(Emulsion, oil in water)兩種劑型後，分別測試以水懸劑 SC(Suspension concentrate)與 微乳劑 ME(Micro- emulsion) 混合製備之濃懸劑型 SE(Suspo-Emulsion)；以及水懸劑 SC(Suspension concentrate)與水基乳劑 EW(Emulsion, oil in water)所混合製備之濃懸劑型 SE(Suspo-Emulsion)。
所製備之微乳劑 ME(Micro- emulsion)及水基乳劑 EW(Emulsion, oil in water)兩種劑型，測試以非離子型界面活性劑混配，並選擇適合之親水親油平衡值(hydrophilic-lipophilic balance，HLB)後，分別與水懸劑 SC(Suspension concentrate)製備之濃懸劑型 SE(Suspo-Emulsion)，以樣品之有效成分，在室溫及耐熱下之分解率；以及觀察樣品在室溫、耐熱及耐冷後之外觀變化，並以樣品之粒徑變化為安定性之指標，操作變因包括：界面活性劑及HLB值。
以水懸劑 SC(Suspension concentrate)與 微乳劑 ME(Micro- emulsion) 混合製備之濃懸劑型 SE(Suspo-Emulsion)之安定性分析結果，在54

關鍵字

濃懸劑型

並列摘要

This experimental choice tech：Pencycuron in field have DP(Dustable powder)、SC(Suspension concentrate)、WP(Wettable powder) and so on three kind of formulations. Difenoconazole in field have EC(Emulsifiable concentrate)、SC(Suspension concentrate)、WG(Water dispersible granules) and so on three kind of formulations.For the friendliness environment nowadays employs the formulation. Promotion medicament and save labor.Test Pencycuron preparation SC(Suspension concentrate) and Difenoconazole preparation ME(Micro- emulsion) and EW(Emulsion, oil in water). Distinction test SC(Suspension concentrate) with ME(Micro- emulsion) preparation SE(Suspo-Emulsion) and SC(Suspension concentrate) with EW(Emulsion, oil in water) preparation SE(Suspo-Emulsion).
ME(Micro- emulsion) and EW(Emulsion, oil in water) mixes matches non-ionic surfactant,and test hydrophilic-lipophilic balance. Observation effective component. In room temperature and heat-resisting under rate of dissociation and appearance. The operation changes including hydrophilic-lipophilic balance and surfactant.In SC(Suspension concentrate) with ME(Micro- emulsion) preparation SE(Suspo-Emulsion) rate of dissociation 2.16% and 1.62%,less than 5%.
Result demonstration particle size analysis chart. SC(Suspension concentrate) with EW(Emulsion, oil in water) preparation SE(Suspo-Emulsion) the particle size is 27.795

並列關鍵字

Suspo-Emulsion

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