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  • 學位論文

以體阻抗容積描繪法探討脈搏傳導時間與血壓相關性的研究

Evaluation of Relation between Pulse Transmission Time and Blood Pressure Using Impedance-plethysmography Technique

指導教授 : 劉省宏
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摘要


隨著科技的進步,許多生理監控(physiological monitoring)的儀器逐漸轉換成穿戴式裝置(wearable devices),但目前市面上的血壓儀都是臂帶式的充氣裝置,測量時的臂戴高壓,常讓使用者感到不適,為了減輕使用者的不適,且能測量動態的血壓值,本研究目的在發展體阻抗容積描繪法(impedance-plethysmography, IPG)的測量技術,配合心電描繪法(electrocardiography, ECG),測量脈搏傳導時間(pulse transmission time, PTT),進而評估出血壓值。本研究的實驗,將與傳統光容積測量技術進行比對,實證我們提出的體阻抗容積測量技術,是可以實現以無臂帶式的血壓測量方法。實驗中有20人參與,透過運動讓受測者的血壓產生改變,實驗結果顯示,以傳統光容積測量技術的收縮壓與脈搏傳遞時間的相關度為γ=0.77。以體阻抗容積測量技術的收縮壓與脈搏傳遞時間的相關度為γ=0.68。當收縮壓越高時脈搏傳導時間越短,反之收縮壓越低時脈搏傳導時間越長,因此本研究證明體阻抗容積測量技術可以取代傳統光容積測量技術。

並列摘要


With the advancement of science and technology, many instruments of physiological monitoring are gradually converted into wearable devices. However, current blood pressure monitors in the market all use a cuff to measure blood pressure. Users feel uncomfortable when they are measuring. In order to reduce the user's uncomforting, and use it on daily life or exercise, in this study, the goal of this study is to develop the impedance-plethysmography and electrocardiography techniques to measure the pulse transmission time (PTT). Then, PTT could be used to evaluate the systolic blood pressure. Twenty subjects participated in this study. They were asked to do the exercise to arise their blood pressure. The results show the correlation coefficient, γ, between PTT and systolic blood pressure was 0.77 by the photoplethysmography, and the γbetween PTT and systolic blood pressure was 0.68 by the impedance-plethysmography. Moreover, the systolic pressure more high, the PTT more short. Thus, according to our study, the impedance-plethysmography technique could replace the photoplethysmography technique to measure blood pressure.

參考文獻


[1] C. C. Y. Poon and Y. T. Zhang, “Cuff-less and noninvasive measurements of arterial blood pressure by pulse transit time”, 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference, 2005, pp. 5877-5880.
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[3] O. A. Garcia, J. A. Pérez, P. S. Luna and C. Alvarado, “Impedance plethysmography detection with mobile and concealed devices”, IEEE Latin America Transactions, 2016, Vol. 14, No. 4, pp.1638-1644.
[6] D. G. Jang, S. H. Park and M. Hahn, “A gaussian model-based probabilistic approach for pulse transit time estimation”, IEEE Journal of Biomedical and Health Informatics, 2016, Vol. 20, No. 1, pp.128-134.
[8] Texas Instruments, "TL082-N Datasheet", http://www.ti.com/, 2017.

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