- 學位論文
三元Ti-10Zr-X與Ti-20Cr-X合金於牙科應用之研究
A study on the ternary Ti-10Zr-X and Ti-20Cr-X alloys for dental applications
摘要
本研究選用新熔製的三元鈦合金Ti-10Zr-X (X = Nb、Mo、Fe、Cr)及Ti-20Cr-X (X = Nb、Mo、Fe、Zr) 合金為基材，並與純鈦作比較，進行陶瓷燒附強度測試、耐蝕性和生物相容性分析。 第一部分：Ti-10Zr-X合金 陶瓷燒附方面，Ti-10Zr-X合金與陶瓷結合強度範圍為17.49 MPa至22.46 MPa ，其中以Ti-10Zr-Nb合金具有最高結合強度。由SEM/EDS分析經結合強度測試後之金屬表面發現，殘留陶瓷成分屬於結合層，Ti-10Zr-Nb合金表面殘留陶瓷量多於c.p. Ti，而各種Ti-10Zr-X合金之熱膨脹係數 (9.63×10-6 /℃~9.86×10-6 /℃) 都明顯低於Duceratin瓷粉 (12.5×10-6 /℃)，說明無法大幅提升兩者之間的結合強度。耐蝕性方面，Ti-10Zr-X合金和c.p. Ti在不含氟人工唾液中均具有良好之耐蝕性，但是在含氟人工唾液中兩者耐蝕性均會受影響而降低，且隨含氟量愈高影響愈大。以ESCA分析試片表面顯示，Ti-10Zr-X合金表面除發現TiO2，亦發現ZrO2，但是其對Ti-10Zr-X合金在含氟人工唾液中之耐蝕性質似乎沒有助益。生物相容性方面，SEM觀察與MTT assay顯示類骨母細胞 (MG-63) 於各種Ti-10Zr-X合金和c.p. Ti皆具有良好的生物相容性。 第二部分：Ti-20Cr-X合金 陶瓷燒附方面，一系列Ti-20Cr-X合金與陶瓷結合強度皆高於c.p. Ti ，其中以Ti-20Cr-Mo合金具有最高結合強度，各種Ti-20Cr-X合金之熱膨脹係數(11.03×10−6 /℃~11.36×10−6 /℃) 高於c.p. Ti之熱膨脹係數 (10.12×10-6/℃)，其中Ti-20Cr-X合金與Duceratin瓷粉 (12.5×10-6 /℃) 之熱膨脹係數較接近，因此具有較高之結合強度。耐蝕性方面，Ti-20Cr-X合金和c.p. Ti在不含氟人工唾液中均具有良好之耐蝕性，但是在含氟人工唾液中，各種Ti-20Cr-X合金之耐蝕性高於c.p. Ti。ESCA表面分析在各種Ti-20Cr-X合金除發現TiO2，亦發現Cr2O3，有助於提升Ti-20Cr-X合金之耐蝕性。生物相容性方面，SEM觀察與MTT assay顯示MG-63細胞於Ti-20Cr-X合金與c.p. Ti表面皆具有良好的生物相容性。
並列摘要
This research aimed to evaluate the ternary Ti-10Zr-X (X = Nb, Mo, Fe, Cr) and Ti-20Cr-X (X = Nb, Mo, Fe, Zr) alloys, compared with that of commercially pure titanium (c.p. Ti). Included in this evaluation criterion, are the bond strengths between porcelain (Duceratin), their corrosion resistance and their biocompatibility. The Ti-10Zr-X alloys aspect: The results indicate that Ti-10Zr-Nb had the highest bond strength (22.76 MPa), which was higher than that of c.p. Ti (21.1 MPa). In addition, the thermal expansion coefficient (CTE) values of the Ti-10Zr-X alloys were lower than that of Duceratin (12.5×10-6 /℃), and ranged from 9.63×10-6 /℃ to 9.86×10-6 /℃. It would verify the fact that weak bond strength is the result of a mismatch between CTEs. Linear polarization results showed that artificial saliva and that containing NaF resulted in different corrosion behavior in Ti-10Zr-X alloys and c.p.Ti. The Ti-10Zr-X alloys had lower resistance to corrosion in the fluoride-containing artificial saliva than that of c.p. Ti. ESCA results verify that after potentiodynamic polarization, a passive film consisting of TiO2 and ZrO2 formed on the surface of Ti-10Zr-X. The SEM observation and MTT assay indicate that the osteoblast-like cell (MG-63) growth on all Ti-10Zr-X alloys and c.p.Ti showed good biocompatility. The Ti-20Cr-X alloys aspect: The results indicate that Ti-20Cr-Mo had the highest bond strength (31.5 MPa), which was higher than that of c.p. Ti (21.1 MPa). In addition, the CTE values of the Ti-20Cr-X alloys were higher than that of c.p. Ti (10.12×10-6 /℃), and ranged from 11.03×10-6 /℃ to 11.36×10-6 /℃. This indicates the fact that strong bond strength is the result of a closer match between CTEs. Linear polarization results showed that Ti-20Cr-X alloys had better resistance to corrosion in the fluoride-containing artificial saliva than that of c.p. Ti. ESCA results verify that after potentiodynamic polarization, a passive film consisting of TiO2 and Cr2O3 formed on the surface of Ti-20Cr-X. The SEM observation and MTT assay indicate that the osteoblast-like cell (MG-63) growth on all Ti-20Cr-X alloys and c.p.Ti showed good biocompatility.