下顎骨齒源性黏液纖維瘤—病倒報告及文獻回顧

黏液瘤(myxoma)爲一種良性腫瘤。在軟組織中好發生於皮膚、生殖泌尿道、胃腸道等組織，罕見於口腔，另外也常見於心臟之病變。常因浸潤鄰近組織，導致術後復發率高。組織學上，口腔內的黏液瘤屬於纖維組織産生黏液性變性(myxomatous change)，非真正的黏液瘤。齒源性黏液纖維(odontogenic myxofibroma)是由牙胚的間葉組織如牙乳頭(dental papilla)、齒囊(dental follicle)或牙周韌帶(periodontal ligament)所發生。發生年齡多爲10至30歲，無性別差異，下顎較常見；常伴有缺齒或阻生齒。此病灶可使骨膨脹而破化皮質骨，但長生不快。放射線影像呈斑點狀、蜂窩狀或破壞性骨膨大的放射線透射區。手術切除預後雖良好，但復發率高。本病例爲一25歲女性，主訴左下顎骨腫脹。檢查發現左下顎第二小臼齒及第一大白齒間有一腫塊，觸診微痛，牙齦顔色正常。切片證實爲齒源性黏液纖維瘤，幫安排腫瘤切除合併部份下顎骨切除術治療，術後追蹤傷口癒合良好，目前無發現象。

關鍵字

齒源性黏液纖維瘤；黏液瘤；下顎骨切除術

並列摘要

Myxoma is a benign tumor which usually occurs in the heart, skin, urinary tract and stomach. The lesion rarely occurs in the oral cavithy. Because surrounding tissue is often invaded, so high recurrent rate recorded. Histologically, myxoma in oral cavity is usually a myxomatous change of fibrous tissue, so it is not a true myxoma. Odontogenic myxofibroma is arising from the odontogenic mesenchymal tissue like dental papilla, dental follicle and periodonal ligamnet. The predominate age of odontogenic myxofibroma is from ten to thirty. No sex difference and usually occurs at mandible. It will combine with impacted tooth or missing tooth. The tumor grows slowly and the cortical bone is often expanded and destroyed. The prognosis is good but high recurrent rate is reported. This is a case of 25 years old female and the chief complaint is swelling over lower left posterior teeth area. A mass was noted between the second premolar and first molar of left mandibular area. The color of gingival was normal but tenderness was noted over the lesion. Odontogenic myxofibroma was proved after incisional biopsy examination. So the operation of tumor excision combined with marginal mandibulectomy was performed. The wound healing is good and no recurrent.

並列關鍵字

Odontogenic myxofibroma ； myxoma ； mandibulectomy

國際替代計量

下顎骨齒源性黏液纖維瘤—病倒報告及文獻回顧

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