H1N1新型流感之中西醫用藥探討

Application of Traditional Chinese Medicine and Western Medicine to Prevent and Treat the Pandemic H1N1

余依婷(Yi-Ting Yu)

《傳統醫學雜誌》 20卷1期 (2009/10) Pp. 85-104

https://doi.org/10.30038/JTM.200910.0011

摘要

現階段防治H1N1新型流感患者的策略，台灣以西醫為主、中國則採用中西醫結合。西藥選用抗流感病毒藥物克流感或瑞樂沙，兼具治療性及預防性二種臨床用途。中國頒佈的中醫辨證治療方案及中藥預防方案，可直接作為中醫臨床治療參考。本文說明抗流感病毒藥物作用機轉及用藥治療方式，中藥則從具有臨床證據力的中醫藥抗流感研究文獻進行單味中藥及複方方劑之分析，以了解其抗病毒、消炎、調節免疫機制等作用是否符合中醫理論外感熱病的治則。自擬方以具有清熱解毒功效之漱口劑，作為防治H1N1的參考。

關鍵字

流行感冒 ； 抗病毒 ； 抗發炎 ； H1N1 ； 中醫藥

並列摘要

The strategy for preventing and treating the Pandemic (H1N1) 2009 at Taiwan adopts the western medicine methodology, while that in China focuses on the integrated treatment of the Traditional Chinese Medicine (TCM) with western medicine together. Tamiflu and Relenza, the antiviral drugs against influenza A virus, are both clinically effective in prevention and treatment of seasonal or pandemic influenza. China issued the official TCM clinical recommendations and guidelines for prevention and treatment against H1N1, based on the mechanism of the differentiation of symptoms and signs for classification of syndromes in the TCM system. The mechanism and the clinical usage of the anti-influenza virus drugs are elaborated. The PubMed Database and the Cochrane Database of Systematic Reviews are searched to identify the mechanism and clinical evidence of TCM herbs and prescriptions. Their evidence from western anti-virus, anti-inflammation and immuno-modulation model-based mechanisms is compared with the TCM healing mechanism of the ”exterior syndromes”. A new TCM mouthwash preparation of anti-inflammatory and heat-clearing effect based on western medical evidence and TCM principle is proposed for the prevention of pandemic H1N1 influenza.

並列關鍵字

influenza ； anti-virus ； anti-inflammatory ； H1N1 ； TCM Traditional Chinese Medicine