The incidence and prevalence of children suffering from chronic kidney disease in Taiwan is lower than other country, mainly owing to the implementation of urinary screening among children every three years and to massive abdominal sonography executed at gestational age of five months in 1991. Both of the screens aim to discover congenital urinary tract anomaly and hereditary kidney disease. However, there remain few already entered end stage renal disease status while identified. Children are not miniature adults. Such pediatric care requires development needs, recognition of disease, adaptation, mental maturity and peering relationships. Hence we provide medical care from multi-specialists, discuss the treatment goals and render the physical and spiritual support to maintain the life quality of the children and their relatives.