糖尿病相關腎疾病：臨床特徵、危險因子及本土流行病學

Diabetic Kidney Disease: Clinical Features, Risk Factors and Indigenous Epidemiology

江智維(Chih-Wei Chiang) ； 趙家德(Chia-Ter Chao) ； 姜至剛(Chih-Kang Chiang)

《腎臟與透析》 30卷3期 (2018/09) Pp. 109-113

https://doi.org/10.6340/KD.201809_30(3).0002

摘要

糖尿病是造成末期腎病最主要的因子，2015年台灣由於糖尿病導致末期腎臟疾病的患者高達45.3%。糖尿病相關腎病最主要的臨床特徵為腎絲球過濾率下降和白蛋白尿，而白蛋白尿跟腎絲球過濾率下降有很密切的關係；即便如此，不少研究指出，糖尿病患者就算沒有白蛋白尿，還是有可能出現腎絲球過濾率下降的狀況。糖尿病腎病變最主要的兩個危險因子為高血糖與高血壓，如何控制血糖與血壓目前仍是糖尿病腎病變治療的重點。

關鍵字

糖尿病腎病變 ； 臨床特徵 ； 危險因子 ； 流行病學 ； 糖尿病

並列摘要

Diabetes mellitus is the most important predisposing factor for end-stage renal disease. In 2015, the proportion of patients with end-stage renal disease due to diabetes in Taiwan is 45.3%. The main clinical features of diabetic nephropathy include a decrease of estimated glomerular filtration rate (eGFR) and albuminuria, and the latter is significantly associated with the former. However, many studies have suggested that diabetic patients can have a decline of eGFR even if they do not have albuminuria. The predominant risk factors for developing diabetic nephropathy are hyperglycemia and hypertension, and how to control blood glucose and blood pressure has become the centerpiece of treatment for diabetic nephropathy.

並列關鍵字

diabetic kidney disease ； clinical feature ； risk factor ； epidemiology ； diabetes mellitus