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糖尿病相關腎疾病之血壓控制

Blood Pressure Control in Diabetic Kidney Disease

摘要


由糖尿病相關腎疾病之致病機轉可知,腎絲球的高血壓與高濾過(glomerular hypertension and hyperfiltration),以及腎臟內腎素─血管收縮素—醛固酮系統(renin-angiotensin-aldosterone system, RAAS)的過度活化,在糖尿病相關腎疾病的發生與惡化中扮演重要角色;許多臨床研究結果也顯示,血壓控制與抑制過度活化的RAAS在預防及治療糖尿病相關腎疾病中相當重要。

關鍵字

糖尿病 慢性腎臟病 高血壓

並列摘要


Based on the pathophysiology of diabetic kidney disease, glomerular hypertension, glomerular hyperfiltration and overactive renin-angiotensin-aldosterone system (RAAS) play important roles in the occurrence and progression of diabetic kidney disease. There are also many clinical studies showing blood pressure control and inhibition of overactive RAAS are important in the prevention and treatment of diabetic kidney disease.

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