慢性腎衰竭腎骨病變與心臟血管疾病的風險

Cardiovascular Risk in Chronic Kidney Disease-Mineral Bone Disorders

洪麗玉(Lie-Yee Hung) ； 許永和(Yung-Ho Hsu)

《腎臟與透析》 31卷3期 (2019/09) Pp. 118-124

https://doi.org/10.6340/KD.201909_31(3).0004

摘要

多年來慢性腎病（chronic kidney disease, CKD）的流行率一直在增加，而許多慢性腎衰竭病患在還未發生末期腎衰竭（end-stage renal disease, ESRD）之前就因心血管疾病（cardiovascular disease, CVD）而死亡。多種傳統和新型危險因素的存在使這一群患者易於過早發生CVD而死亡。雖然CKD是一種常見的疾病，但對於CKD病患CVD的預防，診斷和治療仍存在爭議。這是因為大多數研究排除了腎功能不全患者，這限制了最佳決策的證據基礎。在這評論性文章中，我們提供了CKD患者介入策略、風險因素、診斷工具和有效管理方案。

關鍵字

慢性腎臟病 ； 心臟血管疾病 ； 慢性腎衰竭腎骨病變

並列摘要

The prevalence of chronic kidney disease (CKD) has been increasing over the years. CKD progresses through stages and it is known that patients are more likely to die than to progress to end-stage renal disease. The presence of multiple classical and novel risk factors predisposes in CKD patients to premature cardiovascular mortality. Prevention, diagnosis and treatment of cardiovascular diseases in CKD are controversies. This is due to the fact that many of the well-established diagnostic modalities and treatment strategies have not been studied in detail in patients with CKD. Most of the studies have excluded patients with renal dysfunction. This has limited the evidence base for optimal decision making. In this review, we aim to cover the risk factors, diagnosis and effectiveness of interventional strategies in patients with CKD.

並列關鍵字

chronic kidney disease ； cardiovascular disease ； chronic kidney disease-mineral bone disorders