透析單位應用鐵劑治療臨床路徑於血液透析病人之有效性

鐵劑治療對於腎性貧血為標準且重要治療方式。在台灣的腎性貧血研究中，建議慢性腎臟病病人在血中鐵蛋白＜300ng/mL或運鐵蛋白飽和度＜30%時，可考慮補充鐵劑，若病人已接受鐵劑治療，要保持鐵蛋白300～500ng/mL，運鐵蛋白飽和度則最好保持30～50%。而導入標準化鐵質治療流程的成效，過去大規模且時間較長的臨床試驗較少。成大醫院血液透析室實施透析病人鐵劑治療的臨床路徑，發現其可以減少紅血球生成素使用劑量及穩定透析病人血紅素及增加血色素達標比率，進而改善腎性貧血的治療效率。

關鍵字

鐵劑治療；腎性貧血；標準化鐵劑治療流程

並列摘要

Iron supplement is standard and important in renal anemia therapy. In renal anemia study in Taiwan, iron supplement is suggested if ferritin less than 300 ng/mL or transferrin saturation less than 30% in patients of chronic kidney disease. For those already with iron therapy, ferritin was suggested to keep in the range of 300-500 ng/mL and transferrin saturation in the range of 30-50%. No large-scale and long period clinical trial investigating efficacy of protocolized iron supplement algorithm was found in the past. In the hemodialysis unit of National Cheng Kung University Hospital, use of iron supplement algorithm could decrease erythropoietin dosage, stabilize dialysis patient hemoglobin, increase patient percentage in adequate hemoglobin range, and further improve renal anemia treatment.

並列關鍵字

iron therapy ； renal anemia ； protocolized iron supplement algorithm

國際替代計量

透析單位應用鐵劑治療臨床路徑於血液透析病人之有效性

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