口服抗凝劑在心房顫動的慢性腎臟病患者之使用

Oral Anticoagulants Usage in Chronic Kidney Disease Patients With Atrial Fibrillation

賴宇軒(Yu-Hsien Lai) ； 徐邦治(Bang-Gee Hsu)

《腎臟與透析》 32卷2期 (2020/06) Pp. 87-91

https://doi.org/10.6340/KD.202006_32(2).0008

摘要

慢性腎臟病患者與腎功能正常的人相比有較高之心房顫動的發生率，同時發生血栓栓塞的風險也是增加的。這些患者之出血風險也相對較高，但是口服抗凝劑對於此族群的益處目前尚未清楚。目前warfarin是最常用的口服抗凝劑，但只有少部分的有心房顫動之透析患者接受口服抗凝劑治療。本文回顧目前在使用中的口服抗凝劑之最新證據，特別是在慢性腎臟病患者相關研究的證據。

關鍵字

心房顫動 ； 口服抗凝劑 ； 慢性腎臟病 ； 末期腎臟病

並列摘要

Patients with chronic kidney disease have a higher incidence of atrial fibrillation than those with normal renal function, and the risk of thromboembolism is also increased. The bleeding risk of these patients is also relatively high, but the benefits of oral anticoagulants for this group are not yet clear. Warfarin is currently the most commonly used oral anticoagulant, and only a small number of dialysis patients with atrial fibrillation receive oral anticoagulant therapy. This article reviews the latest evidence of oral anticoagulants currently in use, especially in studies of patients with chronic kidney disease.

並列關鍵字

atrial fibrillation ； oral anticoagulant ； chronic kidney disease ； end stage renal disease