低蛋白飲食在糖尿病腎病的使用原理與實證

The Principle and Evidence of Low-Protein Diet in Diabetic Nephropathy Patient

林威(Wei Lin) ； 孫樵隱(Chiao-Yin Sun) ； 吳逸文(I-Wen Wu) ； 李進昌(Chin-Chan Lee) ； 許恆榮(Heng Jung Hsu) ； 陳俊宇(Chun-Yu Chen) ； 潘恆之(Heng-Chih Pan)

《腎臟與透析》 34卷3期 (2022/09) Pp. 112-115

https://doi.org/10.6340/KD.202209_34(3).0002

摘要

過去已知低蛋白飲食可以減緩慢性腎臟病的進展，但糖尿病腎病在飲食上的考量較複雜，所以限制蛋白質的效果仍有爭議；蛋白質是構建身體、提供熱量的三大營養素之一，低蛋白質飲食可能增加營養不良的風險，目前糖尿病腎病患者最佳蛋白質攝取量尚未確定；另一方面，酮基類似物應用在糖尿病腎病的效果亦不明確。本篇文章試圖討論低蛋白飲食用於糖尿病腎病的使用原理與實證，並提供臨床上的建議。

關鍵字

糖尿病腎病 ； 低蛋白飲食 ； 酮基類似物

並列摘要

It has been known that a low-protein diet can slow down the progression of chronic kidney disease, while the dietary modification in diabetic kidney disease is more comlex, and the effect of protein restriction is still controversial. Besides, protein is one of the three major nutrients for building the body and providing calories, and low protein diet may also increase the risk of malnutrition, The optimal amount of protein intake in diabetic kidney disease is undefined yet. Besides, the role of ketoanalogue in diabetic nephropathy is also undetermined; this article attempts to discuss the mechanism and evidence of low protein diet in diabetic kidney disease and provide clinical suggestion.

並列關鍵字

Diabetic kidney disease ； low protein diet ； ketoanalogue