慢性腎衰竭蛋白質攝取治療指引更新

Clinical Practice Guideline for Protein Intake in Chronic Kidney Disease

廖述寬(Shuh-Kuan Liau) ； 田亞中(Ya-Chung Tian) ； 張智翔(Chih-Hsiang Chang)

《腎臟與透析》 34卷3期 (2022/09) Pp. 132-136

https://doi.org/10.6340/KD.202209_34(3).0006

摘要

過量的蛋白質攝取被認為是造成腎臟負荷最主要的因素。當腎功能惡化時，蛋白質代謝後所產生的尿毒素會在血液中累積，進而惡化腎功能。此外，過量蛋白質攝取會導致腎臟超過濾（hyperfiltration），也和腎功能惡化有關。因此，對於慢性腎衰竭患者，低蛋白飲食可以同時減少尿毒素產生，並改善腎臟血液動力學，故可能改善臨床症狀及延緩進入維持性透析治療的時間。

關鍵字

低蛋白飲食 ； 營養 ； 慢性腎衰竭

並列摘要

Excess protein intake is a major contributor to kidney overload. When kidney function declines, protein catabolic products (also known as uremic toxin) accumulate in the blood and progressively impair kidney function. Furthermore, excess protein intake may promote renal damage through the renal hyperfiltration response. By reduction in uremia and uremic toxins and an improvement in renal hemodynamics, a reduction in protein intake may reduce clinical symptoms and delay the need for maintenance dialysis treatment.

並列關鍵字

low protein diet ； nutrition ； chronic kidney disease