頭頸部皮脂腺癌－三例報告

Sebaceous Carcinoma of the Head and Neck - Report of Three Cases

許庭碩(Ting-Shuo Hsu) ； 林清榮(Ching-Zong Lin)

《中華民國耳鼻喉科醫學雜誌》 34卷5期 (1999/09) Pp. 418-421

https://doi.org/10.6286/1999.34.5.418

摘要

皮脂腺癌是頭頸部罕見的惡性腫瘤，至今未超過400例病例報告。病灶通常原發於眼瞼板腺，是一高度惡性之癌症，且有頭頸部局部轉移傾向。因其低發生率及外觀上類似良性病變而容易延遲診斷。治療方式以廣手術切為主，合術後放射線治療。本文報告本院耳鼻喉部自1983年至今經歷之3例皮脂腺癌合併頭頸部轉移之病例，討論其特性、診斷及治療，並做文獻之回溯。

關鍵字

瞼板腺 ； 皮脂腺癌

並列摘要

Sebaceous carcinoma is an uncommon head and neck malignancy. Usually, the lesion arises in the meibomian glands of the eyelid and is a malignancy with a high potential of head and neck metastasis. Diagnosis is difficult because of its low incidence and deceptive clinical presentation. Treatment requires wide surgical excision with neck dissection and post-operative irra-diation. Since 1983, we have had three patients with eyelid sebaceous carcinoma and neck masses in our department. Neck dissection was performed for the first and third patients and parotidectomy for the second. Pathological examination all revealed metastatic sebaceous carci-noma. The firs two patients then received post-operative irradiation. In spite of vigorous treatment, the first patient died of multiple bone metas-tases two years later and the last patient showed brain metastasis three months later, only the second showed good result. It is a malignancy with poor prognosis therefore requires clinical alert for early detection and management.

並列關鍵字

meibomian gland ； sebaceous carcinoma