腮腺的惡性淋巴上皮病灶 — 病例報告

惡性淋巴上皮病灶（malignant lymphoepithelial lesion or lymphoepithelial carcinoma）是一種極為罕見的唾液腺腫瘤，臨床症狀和一般的唾液腺腫瘤一樣，都是以硬塊表現。其組織病理和未分化的鼻咽癌（undifferentiated nasopharyngeal carcinoma）不易區分，而此腫瘤又好發在鼻咽癌發生率較高的愛斯基摩人和中國南方。治療方法是以手術切除病灶及術後放射治療為主。本院報告1名25歲男性病患，主訴右腮腺無痛性腫塊約1個月，手術切除後病理報告為惡性淋巴上皮病灶。病患術後接受放射治療，門診追蹤至今18個月沒有復發跡象。由此例可知，在診斷轉移性惡性唾液腺腫瘤，仍須將罕見的惡性淋巴上皮病灶列入鑑別診斷中，且須於診斷前排除鼻咽癌轉移至唾液腺的可能。

關鍵字

惡性淋巴上皮病灶；未分化鼻咽癌；唾液腫瘤

並列摘要

Malignant lymphoepithelial lesion (lymphoepithelial carcinoma) is an extremely rare malignancy of the salivary glands. Clinically, patients typically present with a painless mass in the parotid gland. Histopathologically, it is difficult to differentiate a malignant lymphoepithelial lesion from undifferentiated nasopharyngeal carcinoma. Both malignancies occur more commonly in south-east China and in Eskimo populations. At present, treatment strategies comprise surgical excision of the tumor and postoperative radiotherapy. We describe a 25-year-old man who complained of a painless mass in the right parotid gland of one month’s duration. After surgical excision, malignant lymphoepithelial lesion was diagnosed. Radiation therapy was administered postoperatively. There was no evidence of recurrence or metastasis 18 months after surgery. Malignant lymphoepithelial lesions should be considered in the differential diagnosis of malignant salivary gland tumors, and metastatic undifferentiated nasopharyngeal carcinoma of the salivary glands should be ruled out before making a final diagnosis.

並列關鍵字

malignant lymphoepithelial lesion ； undifferentiated nasopharyngeal carcinoma ； salivary gland neoplasm

國際替代計量

腮腺的惡性淋巴上皮病灶 — 病例報告

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