咽旁間隙之滑膜肉瘤－病例報告

Synovial Sarcoma in the Parapharyngeal Space - Case Report

李俊昌(Chun-Chang Lee) ； 張逸良(Yih-Leong Chang) ； 柯政郁(Jenq-Yuh Ko) ； 洪元宗(Yong-Tsung Hongh) ； 詹光漢(Kuang-Han Chan)

《中華民國耳鼻喉科醫學雜誌》 36卷6期 (2001/10) Pp. 400-403

https://doi.org/10.6286/2001.36.6.400

摘要

頭頸部原發性滑膜肉瘤是相當罕見的惡性腫瘤，尤其是位於重要且結構複雜的咽旁間隙中，在診斷及治療上往往具有挑戰性。本病例報告為一名19歲女性，主訴在左下頜區有一腫塊約有半年之久，病患先前的切片檢查，病理報告為纖維肉瘤，後來經近中線下頜骨切開術將腫瘤完整取出，最後病理報告確定為滑膜肉瘤。術後追加3個療程的化學治療，但病人拒絕接受放射治療。追蹤至今1年，狀況良好，沒有局部復發及肺部、骨骼轉移的現象。由於滑膜肉瘤極具侵襲性，積極的手術治療及術後長期追蹤是相當重要的。

關鍵字

滑膜肉瘤 ； 咽旁間隙

並列摘要

Synovial sarcoma, a malignant soft tissue tumor that primarily occurs in the extremities, is rarely seen in the head and neck. Owing to the anatomical complexity of the head and neck region, a deep seated synovial sarcoma in the parapharyngeal space presents the clinician with something of a diagnostic and therapeutic challenge. In September 2000, a 19-year-old girl presented with an enlarging tumor in the left side of her neck that had grown progressively over the preceding six months. A tumor biopsy performed at another hospital had led to a diagnosis of fibrosarcoma, at which point the patient was referred to our hospital. The tumor was successfully removed via a paramedian mandibular osteotomy. A revised pathological diagnosis of synovial sarcoma was then made. The patient received three courses of chemotherapy with Ifosfamide and Etoposide. Her postoperative course was uneventful and over one-year’s follow-up, no evidence of recurrence or metastasis was found. The poor prognosis for patients with this disease makes aggressive treatment and long-term follow-up important.

並列關鍵字

synovial sarcoma ； parapharyneal space