- 期刊
下唇類基底細胞之鱗狀上皮細胞癌－病例報告
Basaloid Squamous Cell Carcinoma of the Lower Lip - Case Report
摘要
類基底細胞之鱗狀上皮細胞癌是屬於鱗狀上皮細胞癌的一種變異型態。一般而言，好發於頭頸部之聲門上部、梨狀竇和舌根部，文獻中尚未有發生於下唇部的病例報告。本科於1998年3月間經歷一名63歲的男性病人，因下唇部有一5×5 cm呈菜花樣的腫瘤至本院求診，術前頭頸部電腦斷層掃描顯示，左側下唇部腫瘤合併左側下頜部淋巴結轉移，但無遠隔轉移的現象，外院病理組織切片診斷為鱗狀上皮細胞癌。經廣泛性腫瘤切除併頸部淋巴結根除術並以大腿前外側自由皮瓣重建，手術標本之病理組織切片顯示為類基底細胞之驎狀上皮細胞癌且無頸部淋巴結轉移。術後病人拒絕接受放射線治療，追蹤至今3年，並無局部及頸部淋巴結復發或遠隔轉移，亦無第二原發腫瘤的出現。本文綜合過去已發表的文獻，說明類基底細胞之鱗狀上皮細胞癌的臨床特性及病理診斷之依據。
並列摘要
Basaloid squamous cell carcinoma (BSCC) is a histologically distinct variant of squamous cell carcinoma (SCC). The prognosis is usually worse than that of conventional SCC due to early regional cervical lymph node involvement and distant metastases. In general, BSCC seems to have a predilection for the supraglottic larynx, pyriform sinus, and tongue base, but rarely on lip. We describe a 61-year-old man with a 5×5 cm sized, cauliflower-like lower lip mass which was initially diagnosed to be a squamous cell carcinoma and was subsequently referred to our hospital. Pre-operative CT scans of the head and neck showed a left lower lip mass with left submandibular lymph node metastasis. No distant metastases were noted preoperatively. The patient underwent surgical eradication of the neoplasm with selective neck dissection and free anterior lateral thigh flap reconstruction. Surgical pathology led to a diagnosis of BSCC. Post-operative radiotherapy was recommended but patient refused. Neither local recurrence nor distant metastases have been encountered three years after treatment. In this report, a literature review and description of the clinicopathological characteristics of BSCC are presented.
延伸閱讀
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- Cobanoglu, B., Simsek, M., & Senol, S. (2015). Rhabdomyosarcoma of the Upper Lip in an Adult Patient. Case Reports in Medicine, 2015(), 337-339-083. https://doi.org/10.1155/2015/508051