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摘要


背景:突發性耳聾目前尚無一特定有效的治療方式。本研究即針對類固醇和血管擴張劑的療效,以及一些可能影響預後的因素,作統計分析。 方法:經回溯性檢閱病歷,自1994年3月至1998年2月,搜集121例接受高劑量類固醇以及血管擴張劑治療之單側突發性耳聾患者。並以聽力進步程度(Recovery Magnitude)和聽力恢復率(Recov-ery rate)作為評估聽力恢復的指標。 結果:聽力進步平均為21.9 ± 21.7 dB,聽力恢復率平均為44.0% ± 62.6%。其中34名(28.1%)完全恢復,22名(18.2%)顯著改善,21名(17.4%)稍有改善,44名(36.4%)無反應。 結論:延遲治療時間愈短、初診聽障程度愈小、聽力圖上高頻率較低頻率損失程度小、及接受類固醇治療之患者,預後較佳。而其他因子,如血管擴張劑的治療、年齡、是否合併眩暈等,對聽力的恢復並無顯著影響。

並列摘要


BACKGROUND: The study aims at making an epidemiological survey of sudden deaf-ness to define the clinical characteristics of this disease. We focused on the treatment effect of steroid and vasodilator and some possible prognostic factors. METHODS: 121 patients with unilateral sudden deafness who received high dose steroid and/or vasodilator-from Mar. 1994 to Feb. 1998 were reviewed retrospectively. Recovery magnitude and recovery rate were adopted as indexes of hearing recovery. RESULTS: The average recovery magnitude and recovery rate were 21.9 ± 21.7 dB and 44.0% ± 62.6% respectively. There were 34 patients (28.1%) recovered completely, 22 (18.2%) with marked recovery, 21 (17.4%) with moderate recovery and 44 (36.4%) with-out significant improvement. CONCLUSIONS: Good prognostic factors included: the shorter of the time elapsed from the onset of the symptom to the initiation of the treatment, less hearing impairment at the first visit, low-tone hearing loss on the audiogram and treatment with steroid. Other factors, however, didn’t influence the outcome significantly.

並列關鍵字

sudden deafness steroid vasodilator

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