This was a case of thirty-four-year-old female suffered from pain in her right hip due to prolonged cross-legged sitting three days ago. The pain in her right hip increased so she visited our OPD with a difficult walk. The diagnosis of piriformis syndrome was made by the physical examinations and special tests, including a palpable sausage-shaped tender mass over the the hip, a positive piriformis sign, a positive FAIR test, a positive Pace's sign and a negative SLRT. The treatment of Chinese-medicine had included traditional manual therapy and Ru-Yi- Jin-Huang-San for external use. The patient was educated with a home-based stretching program for the hip. One month later, the patient had complete relief of pain in the right hip and full recovery from all active functional deficits. The outcome was satisfying.