The diagnosis of both the clinically palpable ad nonpalpable prostate lesions require tissue diagnosis accordingly. Biopsy is indicated in all patients with suspicious prostate malignancy. Twenty-one patients with hard prostate nodules received transrectal prostate biopsy with the new device---spring loaded gun, five of these patients received biopsy using the Vim-Silverman needle at the same time. The greatest advantage was that all of our patients felt less painful by using the spring loaded gun than by using the Vim-Silverman needle. Blood pressure and pulse rate had no changes after all of our biopsy procedures. No urosepsis occurred. However gross hematuria was noted in all except one of our patients. The specimens taken by the Vim-Silverman needle were larger than the spring loaded gun, but all the specimens were adequate for histopathological examination.