Nasal polyposis is a very common disease, but its accompanying extensive craniofacial involvement is rare. In 1989, we experienced a male patient with nasal polyposis, who complained of diplopia, blurred vision and headache for 2 months. Physical and radiological examinations showed that polyps not only occupied bilateral nasal chambers, and all paranasal sinuses, but also extended to the anterior cranial fossa. Eventually, these problems were relieved by craniotomy, bilateral medial maxillectomy, and frontoethmoidectomy.