Surgical Treatment of Dermatofibrosarcoma Protuberans

突出性皮纖維肉瘤是一種少見，生長於皮膚，呈結節狀突起的間葉腫瘤。腫瘤切除的安全距離，對降低復發率，有決定性的影響。從1979年到1993年，本院共有46例突出性皮纖維肉瘤接受治療，手術方法，均接受局部廣泛切除術，安全切除距離均是3公分，其中33例追蹤時間超過參年，復發率15.15%(5/33)。在我們的病人中，尚未有手術後，參年以上才復發。所以術後追蹤非常重要，尤其是3年內。由以上之分析及文獻之對照可知，手術治療具有良好之效果，放射性治療僅用於不能接受手術之病人。

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並列摘要

Dermatofibrosarcoma protuberans (DFSP) is a rare, slow growing, low grade sarcoma originating in the dermis and subcutaneous tissue with a nodular picture. Decision of safe margin for excision is important for decreasing the recurrence rate. We have 46 patients with the pathological diagnosis of DFSP during the past 15 years (1979-1993). The treatment of choice was wide excision with a safe margin of at least 3cm. Thirty three patients were followed for more than 3 years. The recurrent rate was 15.15% (5/33). In our series there were no recurrence of whom were free from tumor more than 3 years after the first operation. So regular follow up is particularly important in the first 3 years. We conclude from this series, and also from review of the literature, that wide local excision offers an excellent probability of cure, and the radiation therapy is only a reasonable alternation in patients who have unresectable lesions.

並列關鍵字

dermatofibrosarcoma protuberans (DFSP) ； recurrence ； wide local excision

國際替代計量

Surgical Treatment of Dermatofibrosarcoma Protuberans

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