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摘要


胰腺泡癌為一罕見的腫瘤,約占胰臟外分泌腺腫瘤的1%。在文獻上,此種腫瘤較好發於男性,其臨床症狀與一般的胰臟癌相似,並無什麼特殊所在。實驗室檢驗,有時可見不正常的脂肪酶及膽紅素昇高。在本病例,廿三歲女性主訴漸進式的皮膚變黃及上腹部腫瘤約壹個月,經whipple氏手術摘除胰臟頭部約10公分左右的腫瘤,外觀上呈肉色且界限明顯。顯微鏡下,可見濃密的細胞,但缺乏細胞問質。另有典型的線泡和實體狀的生長型態,及具特異性的d-PAS染色陽性反應。其鑑別診斷包括胰島細胞瘤,實體及乳頭狀上皮細胞瘤,胰母細胞瘤等。

關鍵字

腺泡癌 胰臟

並列摘要


Acinar cell carcinoma of the pancreas is a rare neoplasm, accounting for about 1% of pancreatic exocrine tumors. In literature, males outnumbered females. Presenting symptoms, compared with ductal adenocarcinoma, were nonspecific. We reported a case of pancreatic tumor in a 23-year-old woman, who presented as a prominent abdominal mass with jaundice. Laboratory data showed elevation of bilirubin, lipase and CA19-9. Image study including ultrasound and computerized tomography revealed an encapsulated tumor arising from pancreas with common bile duct compression. After operation, acinar cell carcinoma was proved by pathology. The tumor, measuring about 11X 10X 8cm in size, looked fleshy and relatively circumscribed grossly. Microscopically, high cellularity without desmoplastic stroma were noted. Besides, typical acinar and solid patterns of growth were identified with characteristic diastase resistant periodic acid-Schiff staining. The differential diagnosis included islet cell tumor, solid and papillary epithelial neoplasm, pancreatoblastoma and so on.

並列關鍵字

acinar cell carcinoma pancreas

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