An Unusual Image of Acinar Cell Carcinoma of Pancreas: Report of a Case

胰臟腺泡細胞癌及特殊影像表現：一病例報告

邱榮彬(Jung-Pin Chiu) ； 李嘉龍(Chia-Long Lee) ； 黃世鴻(Shih-Hung Huang) ； 吳啓華(Chi-Hwa Wu) ； 凃天健(Tien-Chien Tu)

《臺灣消化醫學雜誌》 23卷2期 (2006/06) Pp. 151-157

https://doi.org/10.6557/GJT.200606_23(2).0006

摘要

在外分泌胰臟腫瘤中，胰臟腺泡細胞癌(ACC)是屬於不常見的，大約占胰臟腫瘤之百分之一至二。好發年齡常見於五十至七十歲。胰臟腺泡細胞癌被定義為癌細胞具有分泌胰臟酵素的腫瘤。這些腫瘤在組織學上的特徵代表腺泡細胞不同分化來源。在腹部電腦斷層的影像上會以胰臟腫瘤合併有外膜包覆及內層鈣化表現。我們報告一個七十九歲的女性病人，她以貧血及胃的外部腫瘤壓迫為表現。腹膜的增厚表現出”omental cake”的外觀。病理切片顯示腺泡細胞的型態，免疫化學染色顯示對cytokeratin和polyclonal CEA以及antitrypsin為陽性反應。最後被診斷為胰臓腺泡細胞癌。

關鍵字

腺泡細胞癌 ； 胰臟

並列摘要

Acinar cell carcinomas (ACCs) are uncommon tumors of the exocrine pancreas, constituting 1% to 2% of all pancreatic neoplasms. They are more common during the 5th through the 7th decades of life. ACCs are defined as carcinomas exhibiting pancreatic enzyme production by neoplastic cells. These tumors have highly characteristic histological features reflecting their acinar derivation. Typically they present as a sizable pancreatic mass with a well-defined enhancing capsule and internal calcification on the image of computed tomography. We report an ACC of pancreas in a 79-year-old female who presented with a 3-cm gastric submucosal mass and a history of anemia initially. The external compression from pancreas exhibited typical acinar morphology. The thickness of peritoneal membrane showed ”omental cake” appearance. Immunohistochemical studies demonstrated strong positive reactivity for cytokeratin, polyclonal CEA and antitrypsin. A complete workup identified a primary pancreatic tumor.

並列關鍵字

acinar cell carcinoma ； pancreas