- 期刊
Transcatheter Arterial Embolization Therapy for Metastatic Neoplasms of the Liver
經導管肝臟動脈栓塞療法應用於肝臓轉移性腫瘤之治療
摘要
肝動脈栓塞療法被應用於32例肝轉移性腫瘤之治療。此方法乃經由血管攝影導管注入(Gelfoam)止血棉至全部肝動脈血流停止為止。栓塞後之追跌電腦斷層攝影發現25例有明顯之腫瘤壞死現象，其中12例由大腸直腸癌轉移，3例乳癌，及3例胃癌。本文並未發現肝轉移性腫瘤其在血管攝影所顯示新生血管之豐富度與栓塞之效果有關。此外，栓塞術不會導致非腫瘤部正常肝組織之壞死現象。作者等認為肝動脈栓塞術可以有效地作為肝臟轉移性腫瘤之治療。
並列摘要
Hepatic transcatheter arterial embolization was performed in 32 patients with metastatic neoplasms in the liver. The procedure required injection of Gelfoam suspension through the transfemorally placed angiographic catheter and aimed to achieve a whole-liver embolization. Prominent necrotic change of the metastatic foci as demonstrated by computed tomography occurred in 25 patients; 12 of 13 from colorectal cancer, 3 of 3 from breast cancer, and 3 of 5 from gastric cancer. Patients with hepatomegaly had regression of the liver size after embolization. Angiographically hypervascular metastatic lesions did not show better response to TAE than hypovascular ones. Epigastralgia, nausea, vomiting, fever, and alteration of liver function were the side effects and these side effects subsided in 1 to 2 weeks. There was no necrotic change of the non-tumorous hepatic parenchyma. We conclude that metastatic hepatic neoplasms may be treated by TAE.
延伸閱讀
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