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神經性類肉瘤病合併中樞性尿崩症-病例報告

Hypothalamus and Hypophyseal Neurosarcoidosis with Central Diabetes Insipidus and Hypopituitarism-A Case Report

摘要


類肉瘤病是一種全身性的疾病其特點表現爲非乾酪性肉芽腫。神經性類肉瘤病是更爲罕見的,它會侵犯腦膜,顱神經,腦下垂體,造成腦下垂體功能低下和中樞性尿崩症。我們報告一位27歲的神經性類肉瘤病病患合併葡萄膜炎,腦下垂體功能低下和尿崩症。經過類固醇,dDAVP和荷爾蒙治療後,病況完全改善。當病患有眼睛,神經症狀及神經內分泌方面的問題時,我們必須考慮到神經性類肉瘤病。在這種情況下,一個完整的神經學、影像學和內分泌功能檢查是需要的。

並列摘要


Sarcoidosis is an idiopathic systemic disease which is characterized by the presence of non-caseating granulomas without infection or malignancy. Neurosarcoidosis is an infrequent finding and can involve meninges, cranial nerves, pituitary gland and rarely causes hypopituitarism and central diabetes insipidus. We report the case of a 27-year-old man with neurosarcoidosis who had uveitis, hypopituitarism and diabetes insipidus. The disease was subsided after steroid, dDAVP and hormone replacement therapy. We should keep this diagnosis in mind when a patient presents with combined ophthalmologic, neurological or neuroendocrinological complaints. A complete neurological examination and image survey may be needed in this type of situation.

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