利用實時四維心臟超音波影像評估左心室之舒張與收縮狀態與左心室功能之關係

在一個心臟週期，四維心臟超音波影像需要18到22個心臟影像的序列，每一個心臟影像序列可以從心內膜的輪廓計算出一個左心室容積。利用容積時間曲線可以簡易的找到舒張末期容積、收縮末期容積以及射血比率，而從容積時間曲線的一次微分計算可以得知最大排血率與最大充血率。在心內膜與心外膜的輪廓是使用動態邊緣模組，利用這些輪廓的資料，可以計算出室壁運動百分率以及室壁厚度百分率。利用左心室容積來探討五個正常人的左心室舒張與收縮狀態與射血比率之關係，發現心室容積變化的斜率大者其射血比率也相對的較好，顯示出左心室腔室在收縮期間所作用的力量較大，而從心室打出去的血液也會相對的多，射血比率與容積變化的斜率相關度(r=0.97)。另外，射血比率與收縮的室壁運動和收縮的室壁厚度參數也有很高度的相關性，相關度分別為(r=-0.95)與(r=0.95)，顯示出腔室在運動時與心肌力在收縮時的功能性越強其射血比率會因此變的越高。

關鍵字

左心室；心臟超音波；動態邊緣模組；室壁運動；室壁厚度

並列摘要

In one heart cycle, 4D echo images data set may include 18-22 frames of cardiac image volume. For each cardiac image volume frame, one LV volume can be calculated from the delineated endocardial contour and the LV chamber volume and myocardial volume can be totaled from area of each image slice using Simpson’s rule. Using volume-time curve (VTC), one may easily found EDV, ESV and EF. The peak ejection rate (PER), peak filling rate (PFR) can be calculated from the first derivative of VTC. The tracing of endocardium and epicardium were using active contour model (ACM) with cubic spline. Using these contour data, the percent of wall motion and percent of wall thickening were calculated and tabulated with the volume information. In examining the EF with the slope of the volume change in cardiac cycle, the ventricle having a better EF will be having a larger slope of the volume change. The EF correlate with the slope of the volume change (r=0.97). Besides, the ventricle having a better EF will be having a larger chamber motion and myocardial contraction. The EF correlate with percent systolic wall motion (r=-0.95) and percent systolic wall thickening (r=0.95).

並列關鍵字

left ventricle ； echocardiography image ； active contour model ； wall motion ； wall thickening

國際替代計量

利用實時四維心臟超音波影像評估左心室之舒張與收縮狀態與左心室功能之關係

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