Preparation and Cell Culture Test of Sintered β-Tricalciumphosphate Bioceramics

燒結性三鈣磷鹽陶瓷之製備與生醫活性研究

林峰輝(Feng-Huei Lin) ； 洪敏雄(Min-Hsiung Hon) ； 共義侑(Yi-You Huang)

《華岡工程學報》 5期 (1991/07) Pp. 81-89

https://doi.org/10.29987/CCUHKJE.199107.0003

摘要

本研究利用磷酸鈉鹽添加入三鈣磷酸鹽中，傳統燒結方式，改進燒結體的機械強度，做爲生物體的補骨材料。所研製之材料以骨髓瘤細胞之培養，評估其生物適應性，同時以X-光燒射分析儀、掃瞄式電子顯微鏡及電子微探分析儀，對材料之晶相、顯微結構及成份進行研究及分析。
研究結果，以5wt%磷酸鈉鹽添加入三鈣磷酸鹽中的效果最好，抗張強度及抗壓強度分別高達64MPa及704MPa，理論密度達97%，而且材料擁有極佳的生物適應性。

並列摘要

The effects of Na4P2O7.10H2O addition on the mechanical properities of β-tricalciumphoshpate were studied by the conventional sintering method. Thereafter followed a treatment of materials on NS-1 cell testing to estimate the biological aspects of β-TCP implants. Simultaneously, the effects of additives on the microstructure of the materials were observed by the scanning electron microscope, electron probe microanalysis and X-ray diffractometer.
The results revealed that with the 5wt% Na4P2O7.10H2O addition the tensile strength reached 64MPa, the compressive strenght was 705 MPa, and the densification was 97% T.D. in β-TCP. The biocompatibility studies were satisfied with NS-1 cell testing.