Chondrosarcoma of the Maxilla-A Case Report

上顎軟骨肉瘤－病例報告

黃正鈞(Cheng-Chun Huang) ； 黃振勳(Jehn-Shyun Huang) ； 王東堯(Tung-Yiu Wong) ； 陳畊仲(Ken-Chung Chen) ； 黃則達(Tze-Ta Huang)

《臺灣口腔顎面外科學會雜誌》 25卷3期 (2014/09) Pp. 211-220

摘要

軟骨肉瘤是一種罕見並且潛藏著致命可能性的惡性腫瘤，發生在頭頸部的軟骨肉瘤更是少見。此種疾病好發在四十到五十歲之間的患者群，並且男性患者較為偏多。臨床上常見的症狀是一個無痛的腫塊。軟骨肉瘤的診斷分類是依造病理組織切片所觀察到的惡性軟骨細胞分化的程度來做鑑別診斷。一般而言，軟骨肉瘤最理想的治療方式是以將病灶完整切除為首選。輔助性的放射線治療與化學治療其成效並無法準確預期。本病歷是一位患有上顎軟骨肉瘤的四十六歲女性。此患者接受廣泛性病兆切除手術並且經病理報告證實為低惡性度的軟骨肉瘤。追蹤至今並無復發現象。本文探討軟骨肉瘤在臨床和病理組織學上的特徵與回顧相關之文獻，並且強調組織學上分化的程度與治療方式的選擇對於此種疾病預後之重要性。

關鍵字

軟骨肉瘤 ； 骨腫瘤 ； 上顎 ； 惡性程度

並列摘要

Chondrosarcoma is a rare and potentially fatal malignant tumor, which is even more uncommon in the head and neck region. The affected patients are largely in the fourth decade of lift, with a slight predilection for male patients. A painless swelling is commonly the most frequent complaint. The diagnosis of chondrosarcoma is based on histopathological pattern of malignant chondroid tissue proliferation. Surgical intervention with en-bloc resection is the preferred treatment modality. The outcomes of adjuvant radiotherapy and chemotherapy are usually unpredictable. In the present article, we report a case of low-grade chondrosarcoma of the maxilla in a 46-year-old female patient. She underwent operation of radical excision and is free of disease 30 months after the treatment. We reported the clinicopathological findings of this case and reviewed the literature published previously. This report emphasizes the importance of histological tumor grade and appropriate treatment for the prognosis.

並列關鍵字

Chondrosarcoma ； Bone tumor ； Maxilla ； Grade of malignancy