Carcinoma ex Pleomorphic Adenoma of Right Hard Palate-A Case Report

右側硬腭之多型性腺瘤中癌－病例報告

陳珮吟(Pei-Yin Chen) ； 吳伯璋(Buor-Chang Wu)

《臺灣口腔顎面外科學會雜誌》 26卷4期 (2015/12) Pp. 300-309

摘要

多型性腺瘤中癌是一種罕見，具侵犯性，尚未充分了解的一種惡性唾液腺疾病，特別是在小唾液腺中更少。絕大多數的病例都發生於大唾液腺中，最好發的部位是腮腺，其次為下顎下腺，小唾液腺則非常罕見。多型性腺瘤中癌的臨床表徵跟多型性腺瘤很相近，所以術前很難做出正確的診斷，必須要經由病理切片的判斷才能診斷，所以病理切片是為此疾病最標準的診斷工具。多型性腺瘤中癌的治療，目前仍以手術搭配放射線治療為主。本病例為一個45歲之男性，自述於發現右側硬腭有一無痛腫脹數個月，並且在腫脹的中央處有潰瘍的發生，經由口內切除此病灶，並於腫瘤邊緣並留有五公厘的安全距離。術後追蹤一年至今，在門診追蹤並沒有腫瘤復發的狀況。

關鍵字

多型性腺瘤中癌 ； 小唾液腺

並列摘要

Carcinoma ex pleomorphic adenoma (CXPA) is a rare malignancy of salivary glands. This type of tumor usually arises in major salivary glands, most commonly in parotid gland, which is followed by submandibular gland. CXPA arising in minor salivary glands is extremely rare. CXPA is very difficult to identify before surgical excision for pathologic examination. It is because the clinical features of many cases are similar to those of pleomorphic adenomas (PA). Pathological examination is still the gold standard for diagnosis that-based on the identification of both components of pleomorphic adenoma and carcinoma in the tumor entities. Surgical ablation combined radiation therapy are still the major treatment modalities of CXPA.Here we presented a case of 45 y/o male who had a painless mass with central ulcer on right palatal mucosa noted for several months. The tumor was excised with 5mm safe margin by transoral approach. There was no recurrence during the one year follow-up period.

並列關鍵字

Carcinoma ex pleomorphic adenoma ； Minor salivary gland