中醫脈學臨床研究之回顧―脈搏諧波頻譜分析

Clinic Research Review on Pulse Study in Traditional Chinese Medicine Analysis of the Pulse Harmonic Frequency Spectrum

呂萬安(Wan-An Lu)

《生命學報》 1期 (2006/06) Pp. 55-65

https://doi.org/10.6408/JLS.200606.0055

摘要

分析肝機能的各項現代醫學檢查，包括“SGPT、SGOT、D-Bil、T-Bil、Alp、r-GT、ZTT、CHO、Alb、Alb/Glo”以及超音波檢查，與6種脈搏諧波頻譜指標的關聯性，頻譜指標分別為“C1≧3+且C1+C4≧4+或C1+C6≧4+（振幅），C1≧3-（振幅），C6≧3+且C1+C6≧4+（振幅），C6≦2-（振幅）且C6≦2-（相位角）,C1≧2+且C3≦2-（振幅）或C3≦2-（相位角），C3≦2-（振幅）且C3≦2-（相位角）”。已知85位疑似肝病患者中，檢驗得到兩組統計資料的P值小於0.001，Kappa值＝0.64，進一步從223位疑似肝病患者中檢驗得到兩組統計資料的P值也小於0.001，Kappa值＝0.68，此外24位經現代醫學確診為肝硬化患者，所有患者都出現相同的一種脈搏諧波頻譜指標：C3（脾）≦2-（振幅以及相位角），從生理來看足見脾與較嚴重的肝病具有密切關係，換言之肝病的病程發展之中最後影響脾的功能。這樣的結果與醫聖張仲景在《金匱要略》中所提出的見解「上工治未病，見肝之病，知肝傳脾」是一致的，值得進一步深入探討。

關鍵字

脈波頻譜

並列摘要

Correlation between liver tests, which include SGPT, SGOT, D-Bil, T-Bil, Alp, r-GT, ZTT, CHO, Alb, Alb/Glo, ultra sound scanning, and pulse harmonic frequency spectrum were analyzed. We used the following 6 criteria of pulse harmonic frequency spectrum for diagnosis as liver abnormality to test the correlation: (1) C1≧3+ and C1+C4≧4+ or C1+C6≧4+ (in intensity); (2) C1≧3 (in intensity); (3) C6≧3 and C1+C6≧4 (in intensity); (4) C6≦-2 (in intensity) and C6≦-2 (in the phase)and (5) C1≧2+ and C3≦-2 (in intensity)or C3≦-2 (in the phase); (6) C3≦-2 (in intensity) and C3≦-2 (in the phase). We considered only 6 criteria for liver abnormality of 85 patients with possible liver diseases, the correlation was high with p＜0.001, Kappa=0.64. We further approved the same 6 criteria for liver abnormality of 223 patients with possible liver diseases, the correlation was more and more high with p＜0.001, Kappa=0.68. Other study show that 24 cirrhosis patients possessed all the same criteria that C3≦-2 (in intensity) and C3≦-2 (in the phase). Above all the studies we found that the special importance of the spleen in severe liver diseases such as cirrhosis. This finding suggests that the spleen being closely related to the liver in physiology and pathology especial on the terminal stage of liver diseases. These understandings were consistent with the teachings by Chung-Ching, Chang who stated in Chin-Kuei-Yao-Lueh that ”the superior physician knows that liver disease eventually transmits to the spleen meridian”. It was worth to research into in depth.

並列關鍵字

pulse ； spectrum

參考文獻

鄧鐵濤編(1998)。中醫診斷學。台北:知音出版社。

戴新民編(1986)。難經今解。台北:?業書局。

李培生編(1995)。傷寒論。台北:知音出版社。

Lu WA,Cheng CH,Wang Lin YY(1996).Pulse spectrum analysis of hospital patients with possible liver problems.Am J Chin Med.24,315-322.

Lu WA,Wang Lin YY,Wang WK(1999).Pulse spectrum analysis of the cirrhosis patient.IEEE Eng in Med and Bio Magazine.18,73-75.