以人造皮修補頰黏膜癌術後缺損－病例報告

Repaired the Buccal Cancer Post-Excision Defect with Artificial Dermis-A Case Report

張明智(Ming-Chih Chang) ； 吳宗隆(Tsung-Lung Wu) ； 陳錦松(Chin-Sung Chen) ； 莊世昌(Shih-Chang Chuang)

《中華民國家庭牙醫學雜誌》 4卷4期 (2010/03) Pp. 45-49

https://doi.org/10.6566/JFD/2010.4(4).45

摘要

59歲具抽菸及喝酒習慣之男性病患因右頰黏膜潰瘍長期不癒，輾轉來到本院求診，經病理切片手術證實為鱗狀細胞癌，綜合各項檢查診斷為癌症分期第二期。安排於全身麻醉下進行病赴廣泛性切除手術，並以人造皮進行術後缺損修補，術後病理報告顯示為分化良好型之鱗狀細胞癌，檢體邊緣無癌細胞，完全切除。住院期間病患並無特別不過感，傷口癒合良好，依計劃於術後第七天拆線，第八天出院。病患出院後定期複診，目前追蹤已近四個月，無頸部淋巴轉移，口內亦無復發之情形。對於早期口腔癌術後缺損之修補，人造皮為不同於自體皮膚移植之另一選擇。

關鍵字

鱗狀細胞癌 ； 人造皮

並列摘要

A case of 59 y/o male with alcohol and betel quid chewing habits, he came to our out patient department due to unhealed ulcer over right side buccal mucosa for about 6 months. Biopsy was done and histopathologic report was ”squamous cell carcinoma”. After specify surveys were done, he was diagnosed as T2N0M0, cancer stage Ⅱ. Wide excision was performed under general anesthesia and the defect was repaired with artificial dermis. Surgical histopathologic report was ”well-differentiated squamous cell carcinoma” and the specimen margin was free of malignant cell. Patient did not feel any significant discomfort during admission. The wound healing was uneventful and he was discharged as schedule. Patient received regular follow up after discharged. No evidence of intraoral recurrence and neck metastasia on post-operation 4(superscript th) visit. Compared to autogenous skin graft, artificial dermis is also a good choice for early stage oral cancer post-excision defect repaire.

並列關鍵字

squamous cell carcinoma ； artificial dermis