矽基雙酚A分子拓印聚合物材料製備及其反蛋白石結構之感測應用

Fabrication of Silicon-based Molecularly Imprinted Polymers as Inverse Opal Film for Sensing Bisphenol A

徐樹剛(Shu-Kang, Hsu) ； 張淑閔(Sue-min, Chang) ； 李俊錡(Chun-chi, Lee) ； 張昭君(Zhao-Jun, Chang)

《中華科技大學學報》 71期 (2017/07) Pp. 1-17

摘要

雙酚A(Bisphenol A)為製造塑膠製品常使用之原料，國際間普遍認為其具環境荷爾蒙物質特性。本研究以分子拓印聚合物(molecularly imprinted polymers,MIPs)技術，製備出對BPA 具有良好選擇性吸附能力之矽基MIP 材料，並以聚苯乙烯微米球自組裝之模板，將其製成具光子晶體特性之反蛋白石結構，藉由材料吸附BPA 後，整體折射率改變並造成反射光波長偏移特性，進行水中BPA 濃度感測。本研究所製備的BPA 矽基拓印材料對標的物具高拓印因子(α=10.5)，相對於結構類似物4-叔丁基苯酚(4-tert-Butyl phenol, 4-BP)，選擇性係數(β)可高達3.94，以此拓印材料製得的反蛋白石感測元件可於10 分鐘內響應分析物濃度，並對水中BPA 濃度1 - 100 mg/L 範圍具訊號線性關係(R^2=0.974)，相關結果可作為未來開發矽基MIP 反蛋白石光學感測器參考。

關鍵字

雙酚A ； 分子拓印聚合物 ； 光子晶體 ； 反蛋白石

並列摘要

Bisphenol A (BPA), being considered as one of environmental hormones, is commonly used for manufacturing plastic products. In this study, a silicon-based molecularly imprinted polymer (MIP) with good selectivity for BPA was fabricated, and it was also constructed as inverse opal film (IOF), a kind of photonic crystal, by using polystyrene microsphere opal templates. The reflection wavelength of inverse opal film will be shifted after BPA adsorption due the overall refractive index of MIP changed. Compared with the analog compound of 4-tert-Butyl phenol (4-BP), the imprinting factor (α) and selectivity coefficient (β) of the BPA silicon-based MIP prepared in this study are 10.5 and 3.94, respectively. The responsive time of MIP-IOF sensing for BPA is within 10 minutes and has a signal linearity (R^2 = 0.974) for the BPA concentration in the range of 1 - 100 mg / L. The results can be used as a reference for the development of silicon-based MIP-IOP optical sensor in environmental applications.

並列關鍵字

bisphenol A ； molecularly imprinted polymers ； photonic crystals ； inverse opal