This study attempts to explore in depth the relations between reading comprehension and vocabulary acquisition in the setting of vocational college. In language acquisition, evidence from research literature and the prevailing notion from language practitioners and learners suggest that vocabulary plays a significant role in reading comprehension. A great amount of time has been devoted to vocabulary teaching and learning. However, different vocabulary pedagogies might affect various phases of vocabulary acquisition and reading comprehension in learning processes. Relations between reading and vocabulary are multi-dimensional; the notion that vocabulary teaching and learning boost reading comprehension is further explored and specified in this study. This paper reveals the intriguing connections by exploring effects that different proportions of reading and vocabulary teaching and practice have on learners, performance in a vocational college. Subjects of the study were learners from an English language class; they have taken pre- and posttests on reading comprehension and vocabulary over an academic year. In this language class, the amount of time paid to vocabulary learning outweighed that given to reading comprehension. The study found positive and significant differences appear among learners' reading comprehension and vocabulary learning outcomes in this class setting in which more class time focused on vocabulary teaching and practice. This paper clarifies hidden assumptions between reading comprehension and vocabulary and further provides practical implications contributed to reading comprehension and vocabulary teaching and learning in the vocational education system.