Hospitalized pregnant woman experiences overwhelmed physical and psychological stress. Once tocolysis is failed, most of patients experienced extreme loss that may emotionally threaten her maternal role. The purpose of this article describes a pregnant woman, who had experienced miscarriages twice, is now facing the fact of tocolysis failure at the gestational age of 20 weeks. The nursing period care was from August 14th to 19th, 2013. The nursing process was based on Gordon's 11-item functional health assessment of health problems. The woman's health problems were identified as the following: anxiety/uncertainty about tocolysis; impaired comfort /medical treatment and anticipatory; grief/losing expectant fetus during the nursing care process. During the nursing period, the author explored patient's needs actively, gave recognition and support for the pregnant woman, provided family-centered care, memory of losing expectant fetus and discharge care services. The woman finally could cope with the grief of fetus loss.