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  • 學位論文

脊髓損傷病患起坐性暈眩程度與血壓 及血氧濃度關係之研究

Relationship between Orthostatic Presyncope Symptoms and The Signals of Blood Pressure and Oxygen Saturation in Spinal Cord Injury

指導教授 : 張恆雄

摘要


本研究探討脊髓損傷病患之血壓與血氧濃度受受傷程度與傾斜床治療角度的影響,以得到血壓與暈眩程度的關係及血氧濃度與暈眩程度的關係,做為未來傾斜床治療訓練回饋控制系統開發的依據。研究中使用可見視力範圍與病患感覺來量化暈眩程度,取39位脊髓損傷造成四肢癱瘓病患於傾斜床治療訓練時之上臂非侵入式血壓與耳垂血氧濃度加以分析。結果顯示脊髓損傷病患之血壓與血氧濃度受傾斜床治療角度與受傷程度有很大的影響,數據分析時有必要將傾斜床治療角度與受傷程度分組討論。而血壓對暈眩程度的分辨能力僅止於發生暈眩的血壓值與不暈眩的血壓值,血氧濃度則有較佳的分辨能力,對不暈眩、輕度暈眩與重度暈眩間具備有鑑別能力,因此本研究認為血氧濃度可取代血壓成為脊髓損傷病患直立性暈眩與傾斜床治療訓練上新的有效生理訊號,本研究結果期望未來可以做為傾斜床訓練生理回饋的依據。

並列摘要


In this study, the blood pressure and the oxygen saturation of the spinal cord injury (SCI) patients influenced by the severity of injury and the angle of head-up tilt were investingated. It was found that the presyncope symptoms (PS) had something to do with the blood pressure and the oxygen satureation(SpO2). The development of physiological feedback tilt table training system could be based on these results. The eyesight range and feeling of patients were used to quantify presyncope symptoms. Thirty-nine quadriplegic SCI subjects were recruited, in which the mean blood pressure (MBP) and oxygen saturation were measured during tilting up of the head. The results showed that the blood pressure and the SpO2 of SCI patients were influenced by the angle of head-up tilt and severity of injury. For these reasons, the analyzing data of SCI patients during tilt table training might be divided into the different groups of the angle of head-up tilt and severity of injury in statistics. This study had shown that the MBP only could distinguish between symptomatic and asymptomatic, and SpO2 could distinguish among asymptomatic, mild symptoms and severe symptoms. These findings suggest that SpO2 were the physiological signals that were most sensitive to differences in PS, and hence could be used to determine criteria for the optimal biofeedback design of tilt-table training systems aimed at overcoming posture hypotension in SCI patients. These results could be provided as quantitative information of PS for studying the mechanism of orthostatic syncope.

參考文獻


[13] 王顏和,林光華, “脊髓損傷之神經檢查與功能評估” 中華物療誌, 第19卷,第一期,78-86,1994
[5] J. S. Irwin, ”Orthostatic hypotension:Diagnosis and treatment”, Hospital Practice April, pp. 59-69,1984.
[6] P. Engel, G.. Hildebrandt, “Long-term studies about orthostatic traning after high spinal cord injury”, Paraplegia, vol. 14, pp. 159-164, 1976.
[8] F. Gonzalez, J. Y. Chang, K. Banovac, D. Messina, A. A. Martinez, “Autoregulation of cerebral blood flow in patients with orthostatic hypotension after spinal cord injury”, Paraplegia, vol. 29, pp. 1-7, 1991.
[10] B. Pomeranz, R. J. B. Macaulay, et al. “Assessment of autonomic funtion in humans by heart rate spectral analysis.”, Am. J. Physiol., vol. 248(Heart Circ. Physiol., vol. 17), pp. H151-153, 1985.

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