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研究生: 陳巧紋
Chen-Ciao-wen
論文名稱: 山苦瓜葉萃取物對葡聚醣硫酸鈉誘導小鼠腸炎的保護效應與免疫調節之影響
Protective and immunoregulatory effects of wild bitter melon leaf extract on dextran sulfate sodium-induced murine colitis
指導教授: 蔡帛蓉
Tsai, Po-Jung
劉俊仁
Liu, Jun-Jen
學位類別: 碩士
Master
系所名稱: 人類發展與家庭學系
Department of Human Development and Family Studies
論文出版年: 2019
畢業學年度: 107
語文別: 中文
論文頁數: 98
中文關鍵詞: 發炎性腸道疾病山苦瓜葉腸道免疫調節型T淋巴細胞輔助型T淋巴細胞調節免疫
英文關鍵詞: inflammatory bowel disease, wild bitter melon leaf, intestinal immunity, T helper cell, regulatory T cell, DSS-colitis
DOI URL: http://doi.org/10.6345/NTNU201900844
論文種類: 學術論文
相關次數: 點閱:62下載:0
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  • 摘要 縮寫對照表 第一章 文獻回顧 1 第一節、 發炎性腸道疾病 1 第二節、 腸道免疫 6 第三節、 發炎性腸道疾病之實驗動物模式 11 第四節、 山苦瓜的生理活性 15 第二章 研究動機 20 第三章 材料與方法 (MATERIALS & METHODS) 21 第一節、 實驗試劑與設備 21 第二節、 山苦瓜葉樣品製備與組成分分析 23 第三節、 DSS誘導實驗小鼠腸炎 26 第四節、 分析方法與項目 30 第五節、 細胞實驗 38 第六節、 統計分析 40 第四章 結果 41 第一節、 山苦瓜葉萃取物之組成分分析 41 第二節、 實驗(一):預先投予山苦瓜葉樣品再誘發腸炎的實驗模式 44 第三節、 實驗(二):誘導腸炎前後期均給予山苦瓜葉樣品的實驗模式 51 第四節、 TEE 對於 THP-1 細胞 NF-ΚB 的抑制效果 69 第五章 討論與結論 70 第一節、 山苦瓜葉活性成分 70 第二節、 山苦瓜葉緩解 DSS 誘導腸炎的作用 70 第三節、 在不同 DSS 誘導腸炎的模式下比較山苦瓜保護作用 73 第四節、 結論 75 第六章 參考文獻 77

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