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研究生: 羅旭峰
Lo, Hsu-Feng
論文名稱: 開發以LabVIEW程式控制的攜帶型人體呼氣感測裝置之研究
Development of Portable Breath Measurement Device Based on LabVIEW Program
指導教授: 林震煌
Lin, Cheng-Huang
學位類別: 碩士
Master
系所名稱: 化學系
Department of Chemistry
論文出版年: 2020
畢業學年度: 108
語文別: 中文
論文頁數: 76
中文關鍵詞: 自組裝人體呼氣感測裝置氣體感測器人體呼氣肺活量呼吸商
英文關鍵詞: Self-assembly human breath sensing device, Gas sensor, Human breath, Vital capacity, Respiratory quotient
DOI URL: http://doi.org/10.6345/NTNU202000587
論文種類: 學術論文
相關次數: 點閱:50下載:5
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  • 本研究透過自行編寫的LabVIEW程式控制自組裝的氣體感測裝置,並利用此裝置對人體的呼氣進行測量。過往在人體呼氣的研究當中,大多是利用氣相層析質譜儀來對樣品進行分析,雖然氣相層析質譜儀有高靈敏度和高解析度等優點,但儀器本身昂貴龐大無法輕易搬運,而且樣品也需要經過複雜的前處理步驟,因此較不適合應用在即時偵測上,所以本研究選擇使用體積較小操作簡單且價格較便宜的氣體感測器,但氣體感測器一般都是使用在環境的濃度測量當中,無法對氣體樣品的量進行測量,因此將氣體感測器與氣哨聲波技術結合,讓自組裝的呼氣感測裝置的定量分析變為可能。
    在人體深層肺部呼吸和淺層肺部呼吸的實驗結果發現,當受試者在固定的身體條件下進行不同吹氣量的呼氣測試,其呼出氣體的濃度會和呼氣量呈現線性關係,二氧化碳濃度隨著吹氣量增加而上升,反之,氧氣濃度隨著吹氣量增加而下降,並且藉由觀察二氧化碳濃度的線性斜率來了解身體的耗氧能力,也可以間接得知受試者的心肺能力以及肺活量大小。在人體呼氣中二氧化碳濃度與血糖的相關性探討中,從所有受試者的結果可以發現,在喝下糖水後的60分鐘會達到二氧化碳濃度的最大值,並且在喝下糖水後的120分鐘二氧化碳濃度會回復到正常水平,這些變化和口服糖耐力測試的血糖變化趨勢相同,證明了二氧化碳濃度與血糖的相關性,這些結果對於未來開發非侵入性的血糖檢測方法具有一定的潛力。

    In this study, we developed a portable human breath sensing device controlled by LabVIEW program. In the past studies of exhalation, most of them used gas chromatography mass spectrometry to analyze samples. Although the GC-MS is sensitive and resolution, the components are expensive and large. Sample also needs to undergo complicated pre-processing steps, so it is less suitable for real-time detection. We chose to use small size, simple operation, and cheap price gas sensor. However, gas sensors are usually used in the concentration measurement of the environment, and the amount of gas samples cannot be measured. It became possible the gas sensor can allow quantitative analysis because of combined with the whistle sound wave technology. The test of deep and shallow lung breathing found that when subject breath with different insufflation volume under the same body condition, the concentration of exhaled will have a linear relationship with exhalation volume. The carbon dioxide concentration rises with blowing volume. We can also know subject's cardiopulmonary capacity and vital capacity by the linear slope of carbon dioxide. We found after drinking glucose water it will be maximum carbon dioxide concentration in 60 mins, and it will return to normal level in 120 mins. These changes are the same as the blood glucose trend of oral glucose tolerance test. These results prove the correlation between carbon dioxide concentration and blood glucose.

    第一章 緒論 1 1-1研究目的 1 1-2分析物介紹 3 1-2-1人體呼出氣體 3 1-2-2呼氣中的二氧化碳 4 第二章 分析原理及方法 5 2-1市售的氣體感測器 5 2-2光學式氣體感測器 5 2-2-1紅外線吸收介紹 5 2-2-2非散射性紅外線氣體感測器 6 2-3電化學式氣體感測器 7 2-3-1電化學式氣體感測器開發歷史 7 2-3-2電化學式氧氣感測器 8 2-4氣哨聲波感測器技術 9 2-4-1氣哨聲波技術應用 9 2-4-2氣哨發聲原理 10 2-4-3氣哨的設計與製作 10 2-5人體呼氣係數 12 2-6呼吸作用 13 2-7口服糖耐力測試 14 第三章 儀器與實驗方法 15 3-1 LabVIEW 15 3-2自組裝人體呼氣感測裝置 16 3-2-1 ULN2003微型驅動電路 19 3-2-2驅動器ULN2003 20 3-2-3 myDAQ 21 3-2-4繼電器 22 3-2-5二氧化碳感測器CDM7160 23 3-2-6氧氣感測器KE-50 25 3-4人體呼氣感測裝置的LabVIEW程式編制 26 3-5人體呼氣感測裝置的控制主程式與資料處理 33 3-6儀器設備列表 35 3-6-1自組裝人體呼氣感測裝置零件與工具 35 3-6-2藥品列表 38 第四章 研究過程與結果討論 39 4-1人體呼氣感測裝置組裝流程 39 4-2人體呼氣感測裝置的校正 42 4-2-1氧氣感測器的校正 42 4-2-2二氧化碳感測器的校正 44 4-3人體呼氣感測裝置的應用 46 4-3-1人體深層和淺層呼氣的測量 46 4-3-2人體口服糖耐力測試 56 4-3-3呼氣感測裝置在人體呼吸商的應用 61 4-3-4人體呼氣和心率之間的關係 63 第五章 結論 65 參考文獻 66 附錄 72

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