A retrospective cohort study was performed to compare mortality rates of methicillin-resistant (MRSA) and methicillin-susceptible (MSSA) S. aureus bacteremia in intensive care unit (ICU). During the research period, the difference rates of MRSA bacteremia (63.9%) and MSSA bacteremia (20%) was 43.9% (p<.001). Using Kaplan-Meier analysis, the median survial time was on day 12 after onset of MRSA bacteremia and on day 23 after onset of MSSA bacteremia (p<.001). MRSA (Odds ratio 2.75-3.96, p<.05) was an independent prognostic factor for mortality by Cox regression analysis and logistic regression analysis. Conclusion: Our data demonstrated MRSA bacteremia led a higher mortality than MSSA bacteremia in ICU.
A retrospective cohort study was performed to compare mortality rates of methicillin-resistant (MRSA) and methicillin-susceptible (MSSA) S. aureus bacteremia in intensive care unit (ICU). During the research period, the difference rates of MRSA bacteremia (63.9%) and MSSA bacteremia (20%) was 43.9% (p<.001). Using Kaplan-Meier analysis, the median survial time was on day 12 after onset of MRSA bacteremia and on day 23 after onset of MSSA bacteremia (p<.001). MRSA (Odds ratio 2.75-3.96, p<.05) was an independent prognostic factor for mortality by Cox regression analysis and logistic regression analysis. Conclusion: Our data demonstrated MRSA bacteremia led a higher mortality than MSSA bacteremia in ICU.