Since Maurice Duverger proposed the concept of semi-presidentialism in 1980, disputes have increasingly been raised among researchers. Given the gap between norms and operations of semi-presidentialism, as well as the complexities among the relationships of president, prime minister, and congress in the operations of semi-presidential countries, this paper develops a theory-driven comparative framework of this concept. Through reexamining the definitions of semi-presidentialism and the methodology of analyzing its operational types, this paper also discovers the intention and trend among them and explores the independent variables of semi-presidentialism operations to explain the operational types and their transitions. By classifying semi-presidential countries according to their patterns of operational types, this paper not only provides researchers with a more effective model to explain or predict semi-presidentialism operations in different countries, but also assists in solving constitutional problems more effectively.