Lower body mass index is associated with hospital mortality in critically ill Japanese patients

日本危重症患者低体质指数与住院死亡率相关

Tomoaki Yatabe ； Koichi Yamashita ； Masataka Yokoyama

《Asia Pacific Journal of Clinical Nutrition》 25卷3期 (2016/09) Pp. 534-537

https://doi.org/10.6133/apjcn.092015.21

摘要

背景与目的：最近在欧洲重症监护病房（ICU）进行的一项观察性研究表明，体质指数（BMI）与死亡率有关。我们假设日本危重症患者低BMI与住院死亡率增加相关，与在欧洲危重患者中的发现相似。因此，我们在一个ICU回顾性调查BMI 和患者的预后之间的关系。方法与研究设计：我们连续纳入2012年1月到2013年12月之间的ICU患者。根据患者进入ICU时的BMI，将患者分为3组。低体重组（L组）包括BMI低于18.5 kg/m^2的患者，正常体重组（N组）包括BMI介于18.5-24.9 kg/m2之间的患者，超重/肥胖组（H组）包括BMI大于25.0 kg/m^2的患者。回顾性从电子病历中获得患者的资料。结果：共有1,616名住我院ICU的患者。在这些患者中，346名不合格，因此，纳入分析的有1,270名。L组有169名患者，N组有779名患者，H组有322名患者。患者总的死亡率为8.1%，平均住院时间为21天。L组的死亡率显著高于N组和H组（13.6%比7.8%和5.9%，p=0.01）。结论：我们的回顾性研究表明，日本危重患者低体质指数可能与住院死亡率增加有关。

關鍵字

体质指数 ； 结局 ； 死亡率 ； 重症监护病房 ； 日本

並列摘要

Background and Objectives: A recent observational study conducted in European intensive care units (ICU) showed that body mass index (BMI) is associated with mortality. We hypothesized that a lower BMI amongst critically ill Japanese patients was associated with increased hospital mortality, similar to findings noted among critically ill European patients. Therefore, we retrospectively investigated the relationship between BMI and patient outcomes in an ICU. Methods and Study Design: We included consecutive patients who were admitted to our ICU between January 2012 and December 2013. Patients were divided into 3 groups based on their BMI at ICU admission. The underweight (＂lower＂) group (group L) included patients with a BMI below 18.5 kg/m^2, the normal weight group (group N) included patients with a BMI between 18.5 and 24.9 kg/m^2, and the overweight/ obese (＂higher＂) group (group H) included patients with a BMI above 25.0 kg/m^2. Patient data were retrospectively obtained from electronic patient records. Results: A total of 1,616 patients were admitted to our ICU. Of these patients, 346 patients were ineligible, and therefore, 1,270 were included in the analysis. There were 169 patients in group L, 779 patients in group N and 322 patients in group H. Overall, the mortality rate was 8.1% and the median hospital stay was 21 days. The mortality rate in group L was significantly higher than that in both group N and group H (13.6% vs 7.8% vs 5.9%, p=0.01). Conclusions: Our retrospective study suggests that lower body mass index may be associated with increased hospital mortality in critically ill Japanese patients.

並列關鍵字

body mass index ； outcome ； mortality ； intensive care unit ； Japanese