- 期刊
- OpenAccess
添加精胺酸對感染抗甲基青黴素金黃色葡萄球菌小白鼠的影響
Effects of Arginine Supplementation on Methicillin-Resistant Staphylococcus Aureus Infected Mice
摘要
The object of this study was to investigate the effect of arginine supplements on BALB/c mice infected with methicillin resistant Staphylococcus aureus (MRSA). The mice were randomly divided into 3 groups. Each group of mice was fed as follows: 20% Casein diet (Control Group A), 20% Casein diet supplemented with 2% arginine (Group B) and 20% Casein diet supplemented with 4% arginine (Group C). After 10 days of feeding, each mouse was challenged with MRSA organisms intravenously. 20 days later, the survival rate was recorded and anatomic examinations were performed. The colony forming units (CFU) in the kidney and spleen of most of the surviving mice were determined. The result showed that the diet with 2% arginine supplement significantly decreased (p＜0.05) death rate but increased (p＜0.05) spleen weight. The conclusion was that a diet supplemented with arginine would enhance resistance to MRSA infection in the mice.
並列摘要
The object of this study was to investigate the effect of arginine supplements on BALB/c mice infected with methicillin resistant Staphylococcus aureus (MRSA). The mice were randomly divided into 3 groups. Each group of mice was fed as follows: 20% Casein diet (Control Group A), 20% Casein diet supplemented with 2% arginine (Group B) and 20% Casein diet supplemented with 4% arginine (Group C). After 10 days of feeding, each mouse was challenged with MRSA organisms intravenously. 20 days later, the survival rate was recorded and anatomic examinations were performed. The colony forming units (CFU) in the kidney and spleen of most of the surviving mice were determined. The result showed that the diet with 2% arginine supplement significantly decreased (p＜0.05) death rate but increased (p＜0.05) spleen weight. The conclusion was that a diet supplemented with arginine would enhance resistance to MRSA infection in the mice.
延伸閱讀
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